Maeda et al. (Rewiring the Primary Somatosensory cortex in carpal tunnel syndrome) have done some interesting work demonstrating that acupuncture needling is being carefully investigated with regard to the linkage between brain response to acupuncture and the subsequent analgesia, as measured by MRI. Taken together with another paper we are publishing, by Harris et al., Traditional Chinese Acupuncture and placebo (sham) acupuncture are differentiated by their effects on μ-opiod receptors (MORS), it begins to appear that acupuncture processing in the brains of CTS patients differs from that in normal healthy controls. The new evidence suggests that chronic pain patients respond differently, and it may be that the acupuncture actually produces real changes in the receptors.
Please see the links to copies of these papers below:
Rewiring the primary somatosensory cortex incarpal tunnel syndrome with acupuncture by Y. Maeda, H. Kim, N. Kettner, J. Kim, S. Cina, C. Malatesta, J. Gerber, C. McManus, R. Ong-Sutherland, P. Mezzacappa, A. Libby, I. Mawla, L. R. Morse, T. J. Kaptchuk, J. Audette & V. Napadow
Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on μ-opioid receptors (MORs) by R. E. Harris, J-K. Zubieta, D. J. Scott, V. Napadow,R. H. Gracely & D. J. Clauw
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